The Poly Network, a cross-chain DeFi platform, suffered one of the largest hacks in DeFi history stealing over US$600 million worth of cryptocurrencies.
Compound Finance, a leading DeFi lending protocol, experienced a significant exploit due to a bug in a recent upgrade, which resulted in a loss of 490,000 COMP tokens worth approximately US$160 million.
Uranium Finance, a decentralized exchange on the Binance Smart Chain, fell victim to a rug pull, draining approximately US$50 million from the liquidity pools.
AnubisDAO, a decentralized autonomous organization inspired by Dogecoin, conducted a rug pull, for almost US$60 million in Ether.
Although not strictly a DeFi project, the Thodex exchange exit scam in April 2021 had a significant impact on the crypto community, with over US$2 billion in user funds.